Van-Hai Hoang Selected Research

glutaminyl-peptide cyclotransferase

12/2021	Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design.
1/2018	Potent human glutaminyl cyclase inhibitors as potential anti-Alzheimer's agents: Structure-activity relationship study of Arg-mimetic region.
1/2017	Discovery of Potent Human Glutaminyl Cyclase Inhibitors as Anti-Alzheimer's Agents Based on Rational Design.
1/2015	Inhibition of glutaminyl cyclase ameliorates amyloid pathology in an animal model of Alzheimer's disease via the modulation of γ-secretase activity.

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Van-Hai Hoang Research Topics

Disease

6	Alzheimer Disease (Alzheimer's Disease) 06/2022 - 01/2015
2	Triple Negative Breast Neoplasms 01/2022 - 01/2019
2	Amyloid Plaque 01/2018 - 01/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2019
1	Neoplasms (Cancer) 10/2019
1	Neoplasm Metastasis (Metastasis) 10/2019
1	Breast Neoplasms (Breast Cancer) 01/2019
1	Neuralgia (Stump Neuralgia) 08/2014
1	Hyperalgesia 08/2014

Drug/Important Bio-Agent (IBA)

4	glutaminyl-peptide cyclotransferaseIBA 12/2021 - 01/2015
4	Amyloid (Amyloid Fibrils)IBA 12/2021 - 01/2015
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 10/2019 - 01/2019
2	Pyrrolidonecarboxylic Acid (Pyroglutamic Acid)IBA 01/2018 - 01/2017
2	Peptides (Polypeptides)IBA 01/2018 - 01/2017
1	Pharmaceutical PreparationsIBA 06/2022
1	AcetylcholinesteraseIBA 06/2022
1	ElementsIBA 12/2019
1	Proteins (Proteins, Gene)FDA Link 10/2019
1	Antineoplastic Agents (Antineoplastics)IBA 01/2019
1	deguelinIBA 01/2019
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2015
1	Capsaicin (Zostrix)FDA Link 08/2014

Therapy/Procedure

1	Therapeutics 01/2022
1	Induced Hypothermia 08/2014